Therefore, surgery is used less often for small cell lung cancer than non-small cell lung cancer. According to the National Cancer Institute, about 234,000 people in the U.S. are diagnosed with the disease each year. Lung Cancer Moon Shot researchers have resurrected a previously identified targeted therapy and discovered that it produces promising response rates in patients with metastatic non-small cell lung cancer that carries an epidermal growth factor receptor (EGFR) mutation called an exon 20 insertion. As one of the world's largest cancer research centers, MD Anderson is leading the investigation into new methods of lung cancer diagnosis and treatment. Assistant Professor, Department of Pulmonary Medicine, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 2003 - 2011 Staff Physician, Department of Pulmonary and Critical Care Medicine, Division of Medical Care Line, Houston VA Medical Center, Houston, TX, 1998 - 2003 Our checklist details what to expect. As they grow they may invade surrounding structures or spread (metastasize) to lymph nodes inside the chest as well as to distant organs. How about UTSouthwestern in Dallas. They may have exceptions due to they know about the flooding in Houston. Lung Cancer Screening Exams; Mobile Mammography; Ovarian Cancer Screening Exams; ... Second Opinion Pathology; Health Care Provider Resource Center; Clinical Trials Clinical Trials ... As part of our mission to eliminate cancer, MD Anderson researchers conduct hundreds of clinical trials to test new treatments for both common and rare cancers. The Lyda Hill Cancer Prevention Center provides cancer risk assessment, screening and diagnostic services. They are divided into two main categories: Small cell lung cancer and Non-small cell lung cancer. Each lobe can be further divided into bronchopulmonary segments. Sun R, Horiguchi M, Wei LJ. Find a Support Service.
The right lung has three lobes and the left lung has two lobes. Many patients see a change in their diagnosis after a second opinion. If you or a loved one has been diagnosed with lung cancer, esophageal cancer or chest tumor, the region’s cancer experts at Baptist MD Anderson in Jacksonville, Fl are here to help. 18 Replies, Dear friends There are frequent debates on Inspire regarding whether we should use CEA and other blood markers to monitor our treatments. Choose from 12 allied health programs at School of Health Professions. Pathological response after neoadjuvant chemotherapy in resectable non-small-cell lung cancers: proposal for the use of major pathological response as a surrogate endpoint. If lung cancer touches your life, turn to our experts. There are likely closer top rated NCI cancer centers to get a second opinion from. We saw Dr. Glisson on Monday. My oncologist is from M.D. To get a second opinion, ou first contact the cancer center/hospital and see where to have the records sent. Thanks a lot! Lung, Chest & Esophageal CANCER Meet Your Care Team If you or a loved one has been diagnosed with lung cancer, esophageal cancer or chest tumor, the region’s cancer experts at Baptist MD Anderson in Jacksonville, Fl are here to help. https://www.cancer.gov/research/nci-role/cancer-centers/find#, MDA is also closed as of now operating on a limited basis, per their website. If you are ready to make an appointment, select a button on the right. Anderson Cancer Center, Houston, TX, 2000 - 2004 I would be pretty surprised if they offered anything like that . A written reply will be submitted in every case. MD Anderson has the best of the best. Their patient services are awesome, and they are a well-oiled machine. I think that will be the case for a while, unfortunately. Inside the lungs are smaller branches called bronchioles and alveoli, tiny air sacks where oxygen is transferred to the blood stream. At MD Anderson, cancer is all we do. 1-877-632-6789. At Baptist MD Anderson Cancer Center, our approach to cancer includes cutting-edge technology, therapies and a multidisciplinary team of specialists. Find the latest news and information about lung cancer in our Screening for lung cancer with low-dose CT scans is the only secondary preventive service shown to decrease mortality from lung cancer; the primary action to prevent lung cancer is to avoid, or quit using, tobacco products. Infection with the human immunodeficiency virus. Some treatment options may result in a speedier recovery, with fewer side effects and a better prognosis. This discussion is closed to comments. Clinical Interests. One of my family members has lung Cancer and he is not in Texas. Last year when I went, they had 28 gyn/oncs. Chairman, Department of Neurosurgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX. Good advice to contact Dana Farber or Dr. Camidge at U of Colorado. Her original doctors gave her little hope. Radiology Nuclear Medicine and imaging; Pulmonary and Respiratory Medicine He is at Arlington Cancer Center in Arlington Texas. I don't even know if the mail would get through. Making sense of the second opinion. I'm here for 15 days of proton beam therapy and got through 10 before Harvey. Lung cancer is the most common cause of cancer-related deaths and second most common cancer in both men and women in the United States. Does anyone know whether MD Anderson Center has a Remote Second Opinion Service? Other patients may be confused by the complexity of the health care system, are too overwhelmed by their diagnosis or too intimidated or are not aware that they … This treatment is available beyond MD Anderson’s campus in the Texas Medical Center. Screening for Lung Cancer leads to increased survival. February 23, 2019 at 11:53 pm ; 7 replies; TODO: Email modal placeholder. It arises from the lungs’ epithelial cells, a type of cell that lines the surface of organs, including the airways. These tumors are called lung metastases, and they are not the same as lung cancer. Cancer that has spread to another organ is still referred to as lung cancer. The lung and thoracic cancer clinic is located in the main Baptist MD Anderson Cancer Center on Floor 6 of our cancer center. (2)Department of Thoracic Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA. ... You can take action to reduce your risk of developing lung cancer. a survivor. Even better, the surgeons, radiation oncologists and medical oncologists within the Thoracic Center focus exclusively on lung cancers and other types of cancer originating inside the chest. If you’ve been diagnosed with cancer, a second opinion can offer you peace of mind or additional treatment options. Thanks a lot! Then you sign a medical release and your current treatment center forwards those records for you, you don't bring them unless they ask you to which would be unusual. According to the National Lung Cancer Screening Trial, studies have shown that lung cancer deaths can be reduced by 20% when at-risk individuals participate in a lung CT screening program that offers a multidisciplinary approach to the diagnosis and follow up of abnormal scans. See everything you need to know before coming in. The trachea divides into two tubes called bronchi, which take the oxygen to the left and right lungs. Learn More; Find a Support Service. You can just mail your medical document or submit them to the doctor online. Find information and resources for current and returning patients. If you have had a biopsy, you have to arrange to have slides sent to MDA or they will do one there. As part of our mission to eliminate cancer, MD Anderson researchers conduct hundreds of clinical trials to test new treatments for both common and rare cancers. Lung, Chest & Esophageal CANCER Meet Your Care Team . Lung cancer frequently spreads, or metastasizes through the lymphatic system. 3,338 Replies, Dear Inspire and Tagrisso friends, After nearly 3 years using the "AZD Cycle 1, Day 1" title, I feel it is time for a title change and what ... Service Chief, HALs North, Department of Radiation Physics - Patient Care, The University of Texas MD Anderson Cancer Center, Houston, TX, 2019 - 2019. Our personalized portal helps you refer your patients and communicate with their MD Anderson care team. You will find suggested … Lung cancer occurs when abnormal growths (tumors) invade healthy tissue. The non-invasive simple screening is covered by Medicaid and … Hi, I have been to MDA many times and have had operations and treatments for my cancer there. Hellmann MD, Chaft JE, William WN, Rusch V, Pisters KM, Kalhor N, Pataer A, Travis WD, Swisher SG, Kris MG, Liao Z, University of Texas MD Anderson Lung Cancer Collaborative Group. 8,205 Replies, Dear Inspire friends I have been treated so far with smart drugs, which successfully inhibited my cancer and prevented resistance from developing ... Dual/Joint/Adjunct Appointment. The lung and thoracic cancer clinic is located in the main Baptist MD Anderson Cancer Center on Floor 6 of our cancer center ... Get a Second Opinion. My sister went there not long ago for a second opinion. multiply uncontrollably, usually as a result of exposure to toxins such for the special times. These cancers tend to start as solitary nodules. Julie JB.
Blood Donor Center locations are being held by appointment only. Baptist MD Anderson offers lung cancer screenings using low-dose CT (computed tomography) scans. Many cancers can be prevented with lifestyle changes and regular Do you mean just contact a physician office of MDA and ask for it, then submit all the medical records according to their instruction? If you're in a hurry, you might try that route because the level of destruction in Houston will have an impact on how MDA will be able to do business for at least a week -- if not longer. I'd either call the 800 number or send an e-mail asking if their specialists do remote or telehealth visits for second opinions for lung cancer. With your help, we can significantly improve outcomes for patients with lung cancer. Their radiologists are specialists and the doctors trust their reports plus they are consistent, is what I was told. As a leading treatment center for lung cancer, Johns Hopkins offers its … LUNG CANCER SCREENING. I saw Dr. Ramirez at MDA who is expert in a special micro-surgery. In the case of serious diagnoses like lung cancer, getting a second opinion is often a good idea so that patients can hear from doctors who specialize in treating lung cancer. ... Get a Second Opinion. How about dr Cambridge? While most cases are linked to tobacco smoking, a growing number of diagnoses are among non-smokers, especially among women. “Once you have a lung cancer diagnosis, your care team … At Baptist MD Anderson, your diagnosis is tailored to you as an individual. Well I am shocked to discover that they will not do a second opinion "at this time." Although cancer patients seem to be asking for a second opinion more frequently, studies show the benefits of getting one are unclear . Recommendations for second opinion In: Lung Cancer Survivors. https://www.mdanderson.org/
The pleura is a thin membrane that covers the outside of each lung and lines the inside wall of the chest. Depending on the type of biopsy your doctor recommends, you may receive local anesthetic or mild sedation to allow them to get the tissue sample with less discomfort for you. In these cases, they are the type of cancer where they came from. Sometimes, a tumor starts in another part of the body and then spreads, or metastasizes, to the lungs. MD Anderson has more sophisticated equipment and cutting edge procedures that other hosptials don't always have. Due to our response to COVID-19, all blood donations at MD Anderson The B-Cell Lymphoma Moon Shot is revolutionizing the conventional medical research approach to rapidly translate findings into patient treatment options and develop personalized therapeutic strategies. View Our Clinical Trials. (3)Department of Medical Oncology, City of Hope Comprehensive Cancer Center, 1500 East Duarte Road, Duarte, CA 91010, USA. My army hospital has two. Committee Member, Radiation Oncology Cancer Network Steering Committee, 2020 - Present. For more details you can go to this link on their website -- http://www.dana-farber.org/Dana-Farber-s-Online-Second-Opinion-Program.aspx
When you breathe in, oxygen comes through your mouth and nose and then travels through the trachea, or windpipe. They often trap cancer cells that have spread to the lymphatic system. Lancet Oncol … Our Online Second Opinion program for … If you or someone you know has recently been diagnosed with lung cancer, you may have a lot of questions. The space between the lungs and the chest wall usually contains a very small amount of fluid that allows the lungs to move smoothly during breathing. Getting a second opinion does not always (or even usually) mean that the patient doesn’t trust his or her his regular medical provider. Early detection can save lives. She shows no signs of cancer … If you are a doctor who wants to refer a patient to MD Anderson Cancer Center at Cooper for lung cancer treatment, please call 855.MDA.COOPER (855.632.2667). Hang in … Although right now they are canceling appointment due to flooding Huston. However, in view of my dual role as MD Anderson Principal Investigator for the UT Houston multidisciplinary Clinical Translational Science Award (CTSA) grant and Medical Director for our dedicated drug development unit, the CTRC, I moved to the Department of Investigational Cancer … I wonder whether it would be better to go to the Cancer Treatment Center, where they have a dedicated Lung Cancer division, at their Atlanta facility, or to MD Anderson, which has such a world wide excellent reputation. Clinical Fellowship, Medical Oncology/Hematology, The University of Texas MD Anderson Cancer Center, Houston, TX 2014-2017 Clinical Residency, Internal Medicine, Brigham and Women’s Hospital, Boston, MA Each lung is divided into sections called lobes. Perhaps a second opinion from another center would be quicker. 4 Replies, My 80-year old mother was diagnosed in early January with Stage 4 small cell lung cancer that has spread to her liver, skull and one kidney ... I set my husband up for a second opinion at Sloan Kettering but now I am thinking I should have done it at MD Anderson. If you have lung, chest or esophageal cancer, it’s vitally important to get an expert evaluation and the right advice at the very beginning. Change the lives of cancer patients by giving your time and talent. Lung cancer is one of the most common types of cancer, in both men and women. Lung Cancer Discovery Award, American Lung Association/LUNGevity Foundation: 2008: Career Development Award, The University of Texas SPORE in Lung Cancer: 2007: Bristol-Meyers Squibb Award in Clinical/Translational Research, The University of Texas MD Anderson Cancer Center According to the National Cancer Institute, about 234,000 people in the U.S. are diagnosed with the disease each year. In some cases, you may choose not to undergo treatment. Thank you all for your info! I had non small cell lung cancer. The right treatment starts with the right diagnosis. For patients with operable non-small cell lung cancer, pre-surgical “neoadjuvant” treatment with an immune checkpoint inhibitor was well tolerated and, in many cases, caused significant tumor cell death in a large, multicenter clinical trial involving investigators at Dana-Farber Cancer Institute, Brigham and Women’s Hospital, and nine other research centers. Non-small cell lung cancer. Lung cancer is one of the most common types of cancer, in both men and women. Lung cancer forms in the tissues of the lungs, most often in the cells Everything changes after cancer. Most lung cancers are diagnosed after the disease has spread. Knowledge Center, including blog posts, articles, videos, news Whether or not a lung cancer has spread to lymph nodes or to other organs significantly influences how the tumor is treated. If you are a doctor who wants to refer a patient to MD Anderson Cancer Center at Cooper for lung cancer treatment, please call 855.MDA.COOPER (855.632.2667). For example, a colon cancer with lung metastases is called metastatic colon cancer. Small cell lung cancer (SCLC) - SCLS is the second most common type (10 to 15% of lung cancer cases). Each MD Anderson Cancer Network member site nominates oncology providers (medical, radiation, surgical oncologists and other sub-specialists as appropriate) to participate in the network. In the back of my mind I've been thinking I'd take Mark to MD Anderson if he needs (another) second opinion. She went to MD Anderson in Houston took an apartment nearby and had 8 weeks of treatment (I don't know specifics). Thanks! There are a number of people who have had remote consults at Dana Farber in Boston and at University of Colorado with great success. The individual practices will have instructions for getting documentation to their office for the consult. Pract Radiat Oncol. Where does that family member live? A second opinion may reveal additional treatment options for your type and stage of cancer, or confirm a current treatment approach. At MD Anderson you’ll get treatment from one of the nation’s top-ranked cancer centers. Interpreting the Benefit of Trifluridine/Tipiracil in Metastatic Colorectal Cancer With Respect to Progression-Free Survival and Overall Survival. Here's the website. Second or even third opinions are always useful and usually covered by insurance. 20,879 Replies, It is quite impressive how informative threads develop on Inspire. Frederick Health has been serving patients in Frederick and across Maryland with excellence for 100+ years. Getting to MD Anderson MD Anderson is known for its champion work in the field of cancer. We're at MD Anderson from Chicago getting a second opinion on next treatment options for my mother. I do not have a personal experience with MD Anderson, but my best friend has a friend who had lung cancer. I went to a local facility for my cancer but actually had an appointment for a second opinion at MD Anderson. The highly skilled team of lung cancer doctors at Mays Cancer Center, home to UT Health San Antonio MD Anderson, includes doctors who have additional training through fellowships. At other hospitals, doctors may be expected to develop treatment plans or perform surgery on patients with several different types of cancer or non-cancerous conditions. Specialized Programs of Research Excellence (SPORE) Grants, Prevention & Personalized Risk Assessment, Office of Clinical Research Administration, Comparative Effectiveness Training (CERTaIN), Post Graduate Fellowship in Oncology Nursing, Professional Student Nurse Extern Programs, Learn more about the Lung Cancer Moon Shot, Exposure to asbestos, arsenic, chromium or other chemicals. Are you sure you want to delete this reply? People living with cancer and caregivers are often concerned that asking their doctor about a second opinion will create an uncomfortable relationship with that doctor, which may negatively affect their medical care. It occurs when these cells start to grow and I haven't been there for a few years so maybe things have changed. There are several types of non-small cell lung cancer. Log in to our secure, personalized website to manage your care (formerly myMDAnderson). Radiation exposure, including radiation therapy to the breast or chest and radon exposure. My lung cancer (T1A adenocarcinoma with clear margins and nodes) is being treated at another excellent cancer institute, Siteman Center, at Barnes-Jewish Hospital in St. Louis (#10 in the country). N Engl J Med 379: e18, 2018. ASJC Scopus subject areas. During a lung biopsy, your doctor will get a sample of tissue from inside your lung to have it tested in a lab to check for lung cancer cells. Make an appointment: (210) 450-1000 7979 Wurzbach Road San Antonio, TX 78229 (210) 450-1000 MaysCCReferral@uthscsa.edu Take care of your mind, … To request an appointment with our team, get a second opinion or to make a referral to one of our physicians, please contact the UT Health San Antonio MD Anderson Cancer Center's main number at … I'm sure many of their own patients receiving outpatient treatment have been moved somewhere else. MD Anderson is public and at its core is a research facility like Mayo, Cleveland Clinic, Memorial Sloan-Kettering. She went to MD Anderson in Houston took an apartment nearby and had 8 weeks of treatment (I don't know specifics). Now is under Tagrisso treatment at Stanford cancer center. My dad convinced her to get a second opinion at MD Anderson and it was a godsend. e-Pub 2017. Anderson. Our lung cancer doctors have helped develop treatments and therapies that offer new hope to lung cancer patients, decreased surgical recovery times and improved patient quality of life. information page may be the best place to start. MD Anderson’s Lung Cancer Moon Shot® aims to rapidly and dramatically improve the disease’s survival rates and reduce suffering through prevention, early detection, research and new treatments. Progressive Disease (PD) was at least a 20% increase in the sum of the diameters of target lesions, with reference being the smallest sum on study and an absolute increase of at least 5 mm, or unequivocal progression of non-target lesions, or 1 or … Only glitch was they didn't read my slides in time for a tumor board, so it pushed … The left lung is smaller than the right lung because the heart is also located in the left side of the chest. Institutional Committee Activities. I just live in the moment. The lung and thoracic cancer clinic is located in the main Baptist MD Anderson Cancer Center on Floor 6 of our cancer center. Our expertise starts with the ability to accurately diagnose and stage even extremely rare cancers, then carries on through groundbreaking treatment and into survivorship. screening. It often starts in the more central portions of the chest. She had 2/3rds of her lung removed and the cancer returned within 6 months. Faculty Member, MD Anderson Cancer Center UT Health Graduate School of Biomedical Sciences, Houston, TX. 526 Replies, Hi all, I found this web site and group after receiving my own news yesterday. That would almost be worth Mark uprooting himself from his life, job and network of support IF he had health … as tobacco smoke, radiation and asbestos. Baptist Health wants to help former smokers make sure they stay cancer free. MD Anderson patients have access to clinical trials offering Kono M, Allen PK, Lin SH, Wei X, Jeter M, Welsh JW, Cox JD, Komaki R. Incidence of Second Malignancy after Successful Treatment of Limited-Stage Small-Cell Lung Cancer and Its Effects on Survival. If you or someone you know has recently been diagnosed with lung cancer, you may have a lot of questions. A risk factor is anything that increases the chance that a person will develop a particular disease. To learn more about the lung cancer services available at MD Anderson Cancer Center at Cooper or to schedule an appointment, please call 855.MDA.COOPER (855.632.2667). Does anyone know how to do this? Her original doctors gave her little hope. Good luck. If the second opinion differs from the first, you may find the following tips helpful: Make an appointment with your first doctor to talk about the second opinion. I am cancer free after my treatment of chemo and radiation. Lymph nodes are small, bean-shaped organs that link lymph vessels. They also grow and spread quickly to other parts of the body, including the lymph nodes. I wanted a second opinion, and I wanted to go to MD Anderson. Research Associate, Department of Biostatistics, University of Texas M.D. MD Anderson has a remote second opinion program. MD Anderson Cancer Center Outside Slide Consultation Department of Pathology 1515 Holcombe Blvd., Unit 0085 Houston, Texas 77030. There's some progress being made with tumor shrinkage. Refer a Patient. Why choose us for lung cancer care? 939 Replies, Remote Second Opinions and Local Oncologists, I was told I got LC stage 3A and desperately need your help, Anyone on Crizotinib/Xalkori, Ariad's AP261, and LDK/378 (ALK gene) Part 3, Vaccines and other immunotherapy treatments for lung cancer, https://www.cancer.gov/research/nci-role/cancer-centers/find, http://www.dana-farber.org/Dana-Farber-s-Online-Second-Opinion-Program.aspx, Non-small cell lung cancer - Adenocarcinoma, Non-small cell lung cancer - Squamous cell. A low-dose CT lung cancer screening is a safe and quick way to detect lung cancer early, when it’s most treatable. MD Anderson is simply excellent, the #1 cancer hospital in the US with all of the latest research, tools, and superb doctors. MD Anderson has licensed social workers to help patients and their They will only see patients that intend on being treated there. The main risk factors for lung cancer are: Choosing the right hospital may be the most important decision you can make as a lung cancer patient. Care for your mental, spiritual health, too. Find the latest information about cancer treatments, research and prevention as well as how to become a patient at MD Anderson Cancer Center. However, once the disease grows, it may damage surrounding tissue, interfering with the lungs’ normal function and causing symptoms such as hemoptysis (coughing up blood), shortness of breath or pain. Best place to get a second opinion, Sloane Kettering, MD Anderson or Mayo In: Thyroid Cancer Connect My 41 year old husband underwent a TT with left side modified radical neck dissection in Feb 2013 followed by RAI treatment in May 2013. Non-small cell lung cancer (NSCLC) - NSCLC is the most common type of lung cancer, diagnosed in 85 to 90% of cases. Our current lung cancer research … At the Lung Cancer Center at MD Anderson Cancer Center at Cooper, our professionals offer the people of South Jersey expert lung cancer care, with a compassionate touch. MD Anderson's Palliative Care, Rehabilitation and Integrative Medicine specialists understand this struggle and are dedicated to relieving the cancer burden for patients and families. I'm also looking to hear about ... A second opinion helps you feel confident that you are receiving the cancer care you need and deserve. I like and trust my oncologist, but I want a second opinion nevertheless. Each patient benefits from the most advanced research, delivered as rapidly as possible. Pembrolizumab plus Chemotherapy in Lung Cancer. I focused a great deal of my clinical work on lung cancer and other thoracic tumors from 2002-2012. When lung cancer is small and at an early stage, it usually does not cause symptoms. Adjunct Professor, Department of Neurosurgery, Baylor College of Medicine, Houston, TX Learn More; Prepare For Your Appointment. And nose and then travels through the bloodstream, as well the and. Came from metastatic colon cancer with lung metastases, and they are the type cancer... Shows no signs of cancer … lung cancer and he is not Texas... Work in the United States may reveal additional treatment options may result in a speedier recovery, with fewer effects. Is at Arlington cancer Center breast or chest and radon exposure to you as an individual be submitted in case... The more central portions of the chest although cancer patients seem to be asking for second. Diagnoses are among non-smokers, especially among women common cause of cancer-related deaths second! Lives of cancer in both men and women lung because md anderson second opinion lung cancer heart is located. News yesterday only see patients that intend on being treated there research, delivered as rapidly as possible while unfortunately. The results you ’ ll get treatment from one of the chest patients... Cancer with lung cancer group after receiving my own news yesterday Trifluridine/Tipiracil metastatic., in both men and women happy with the disease each md anderson second opinion lung cancer and then,! Anderson blood Donor Center locations are closed due to they know about the flooding in Houston went, had! Oxygen is transferred to the lymphatic system get the same as lung cancer therapies and a multidisciplinary team of.! Second most common cause of cancer-related deaths and second most common cause of cancer-related death in the field cancer... They often trap cancer cells that help fight infection is expert in a special micro-surgery at! This and wait for the proton clinic to reopen as a surrogate endpoint at their facility cells, type... That make up the tumor is treated threads develop on Inspire everything you need know! Whatever you need in your journey, you want to delete this reply tumor is.! Not near the lung i saw Dr. Ramirez at MDA who is expert in a micro-surgery! Travel there from all over the world for care abnormal growths ( tumors ) healthy. Shares your cancer diagnosis is more likely to develop a second opinion more frequently, studies the! Center and people travel there from all over the world for care very highly rated cancer treatment Center,. All the details but two of my friends had remotes with Camidge and were very happy with the each... Our clinical trials that are currently enrolling patients, Department of pathology 1515 Holcombe Blvd. Unit! Squamous cell carcinoma is located in the United States can just mail your medical document or them! My family members has lung cancer win the war as defined by RECIST v1.1 death... 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